GENOVESE LAB - ADVANCED GENETIC ENGINEERING OF HEMATOPOIESIS
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Our Research Environment​

The Genovese Lab is part of a dynamic group of investigators in the Gene Therapy Program of the Dana-Farber/Boston Children’s Cancer and Blood Disorders Center, a joined initiative between the Division of Hematology/Oncology of the Boston Children’s Hospital and the Department of Pediatric Oncology of the Dana-Farber Cancer Institute. This is one of the most extensive and long-running pediatric gene therapy programs in the world, featuring a multidisciplinary team that includes physicians, nurses, researchers, clinical research coordinators, and program administrators. Because our team addresses the full spectrum of gene therapy, from basic research to clinical treatment, our program is continually at the forefront of gene therapy care. Since 2010, the Gene Therapy Program have treated more than 40 patients from 11 countries through 19 gene therapy clinical trials.
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Our research community has a wide breadth of expertise in many areas of basic and translational immunology. We are highly interactive, share new developments at a weekly floor meeting and socialize at a Friday afternoon social hour. The department also have a weekly seminar series in Hematology/Oncology that is widely attended. Our state-of-the-art facilities allow investigation into novel immune mechanisms using cellular, molecular and systems-biology based approaches. 

Friends of the Lab

We actively collaborates with researchers around the world who are interested in developing and applying genetic engineering tools in their work. Combining expertise and sharing tools and technologies helps us achieve greater possibilities. If you are interested in collaborating, please contact us.
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Some of our past and present collaborators are listed below.
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Luigi Naldini, M.D., Ph.D.
Director, San Raffaele Telethon Institute for Gene Therapy (SR-Tiget)
Group leader, Gene transfer technologies and new gene therapy strategies Unit
Group leader, Targeted cancer gene therapy Unit
Full professor, Università Vita-Salute San Raffaele
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Anna Villa, M.D., Ph.D.
Group leader, Pathogenesis and treatment of immune and bone diseases Unit
Director of Research, CNR Institute of Biomedical Technology
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Luigi D. Notarangelo, M.D.
Chief, Laboratory of Clinical Immunology and Microbiology
NIH/NIAID
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Sung-Yun Pai, M.D.
Senior Investigator
Chief,
Immune Deficiency Cellular Therapy Program, Center for Cancer Research, National Cancer Institute
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Franco Locatelli, M.D.
Full Professor of Pediatrics at the University of Pavia
Head of the Department of Paediatric Haematology and Oncology, IRCCS Ospedale Bambino Gesù
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Claire Booth, M.D.
Mahboubian Senior Clinical Lecturer in Gene Therapy
University College of London (UCL)
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Alessandra Biffi, M.D., Ph.D.
Co-Director, Gene Therapy Program 
Lecturer on Pediatrics, Harvard Medical School
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Jean J. Zhao, Ph.D.
Professor, Biological Chemistry and Molecular Pharmacology
Harvard Medical School
Department of Cancer Biology Dana-
Farber Cancer Institute
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Kai W. Wucherpfenning M.D., Ph.D.
Chair, Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute 
Professor of Microbiology and Immunobiology, Harvard Medical School
Professor of Neurology, Brigham and Women's Hospital & Harvard Medical School
Director, Center for Cancer Immunotherapy Research, Dana-Farber Cancer Institute
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©2020 Genovese Lab at Dana-Farber Cancer Institute
  • HOME
  • RESEARCH
    • Hematopoietic Stem Cell Engineering
    • New Cancer Immunotherapies
    • Gene Correction for Inherited Blood Diseases
  • PUBLICATIONS
  • PEOPLE
    • Alumni
  • ENVIRONMENT
  • NEWS
    • Awards
    • Lab Fun
  • JOIN US
  • CONTACT US